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Occupational Therapy

PICO: Asking answerable questions

Most databases are terrible at accepting natural language queries.

When you are searching for evidence for or against a specific treatment, therapy, or intervention, guessing at keywords can be difficult.

PICO is an acronym for:

  • Patient (or population) - what describes the person, condition, or situation?
  • Intervention - What treatment are you looking at?
  • Comparison (or control) - Are you comparing the intervention to another treatment? To a placebo? To a lack of treatment? (The first case is generally easy, the last two might use search terms, or might not use any search terms at all. It can be common to leave this blank when searching for evidence comparing an intervention to placebo or untreated patients)
  • Outcome(s) - Are you looking for improvement in a specific measurable symptom? A reduction in pain? An improvement in strength or mobility or time taken to perform a task? (Sometimes this line might be blank).

PICO is a way of selecting keywords for a database search where the results can help you answer a clinical-style question.

For PICO, mostly this is a yes/no or A/B question: Does intervention A produce a better improvement of symptoms than treatment B? Is treatment C better than placebo? Did this change produce an improvement of symptoms?

PICO is a particularly useful technique for finding quantitative evidence. It will work for qualitative evidence, but keep in mind there are other keyword selection techniques which are sometimes more useful for finding qualitative evidence.

Finding the original evidence

Searching for journal articles in Library databases allows you to build up your own set of evidence when trying to decide whether a specific intervention is useful, or better than another intervention, or worth trying.

Often you will have database access after graduation via your employer, or a direct subscription, or free or open access databases (e.g. PubMed, OTDBASE), or as a benefit of membership in a professional association.

Some databases you might wish to search are:

Pre-digested evidence

Some databases contain the results of existing work where a professional has already searched for evidence and come to a conclusion on best practice based on the evidence discovered.

Such databases usually contain systematic reviews, evidence synopses (also known as evidence summaries), best practice guidelines, and/or clinical practice guidelines.

Sometimes you can find such reviews published as regular journal articles, sometimes you need to check an evidence-based database.

Some databases where you can find these existing evidence reviews and conclusions are: